Neuroblastoma, 1st Edition – FULL INSTANT DOWNLOAD | PDF DOCX EPUB

Name: Neuroblastoma
Edition: 1st Edition
ISBN-13: 9783540408413
ISBN-10: 354040841X
Addition ISBN: 9783540408413, 354040841X
Author(s): NaiKong V. Cheung; ‎Susan L. Cohn, Publisher: Springer, Copyright: 2005
Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.