Biomolecular Interfaces: Interactions, Functions and Drug Design – FULL INSTANT DOWNLOAD | PDF DOCX EPUB

Name: Biomolecular Interfaces: Interactions, Functions and Drug Design
ISBN-13: 9783319168494
ISBN-10: 3319168495
Addition ISBN: 3319168509, 9783319168500, 9783319168494, 3319168495
Author(s): Ariel Fernández Stigliano, Publisher: Springer, Copyright: 2015
The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.