Inflammatory Pathways in Diabetes: Biomarkers and Clinical Correlates – FULL INSTANT DOWNLOAD | PDF DOCX EPUB

Name: Inflammatory Pathways in Diabetes: Biomarkers and Clinical Correlates
ISBN-13: 9783319219264
ISBN-10: 331921926X
Addition ISBN: 3319219278, 9783319219271
Author(s): Author, Publisher: Springer, Copyright: 2015
This book discusses recent advances in new anti- and pro-inflammatory pathways in diabetic disease, and identifies new diagnostic immunological methods that offer potential companion diagnostics for diabetic diseases. New methods in proteomics, mass spectroscopy, immunological assay design, measurement of cellular signal transduction and protease inhibition are used to clarify new biochemical pathways. Biomarker validation in animal models and correlations in humans for diagnostic clinical trials shed new light on the impact of diabetic diseases. The book reviews current understanding of inflammatory pathways in the pathophysiology of insulin resistance, metabolic syndrome, nephritis and other diabetic inflammatory conditions, and is the first to describe the impact of novel adipokines, protease inhibitors and complement markers. By presenting new methodologies for biomarker discovery, it provides a valuable resource for researchers studying clinical diagnosis, drug development, bio-analytical chemistry, proteomics and biochemistry. It is also useful for those conducting clinical and biological studies for targeted drug development. The methodologies and approaches can be applied to other markers, and the information will be helpful in the preparation of research grant applications.