Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine – FULL INSTANT DOWNLOAD | PDF DOCX EPUB

Name: Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine
ISBN-13: 9781493905089
ISBN-10: 1493905082
Addition ISBN: 1493905090, 9781493905096
Publisher: Springer, Copyright: 2014
Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene – KCNJ5 – in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more.