Xenobiotic Metabolism and Disposition : The Design of Studies on Novel Compounds, 1st Edition – FULL INSTANT DOWNLOAD | PDF DOCX EPUB

Name: Xenobiotic Metabolism and Disposition : The Design of Studies on Novel Compounds
Edition: 1st Edition
ISBN-13: 9780849361630
ISBN-10: 084936163X
Addition ISBN: 9780367813093, 9781000714562, 1000722384, 9781000722383
Author(s): Harry P.A. Illing, Publisher: CRC Press, Copyright: 1989
This publication explains the principles of the techniques used in disposition and metabolism studies in animals, in man, and in vitro. It includes methods for studying routes and rates of absorption, distribution, metabolism, and excretion of novel compounds and their metabolites. Relevant surgical, whole-body autoradiographic and pharmacokinetic procedures are discussed, together with techniques for separating and identifying metabolites and metabolic path-ways. Information on when the procedures are appropriate, and examples of what they represent, are presented in order to illustrate the value of such studies.