Name: Athymic Nude Rat Brain Atlas
Edition: 1st Edition
ISBN-13: 9780323997409
ISBN-10: 0323997406
Addition ISBN: 0323997414, 9780323997416
Author(s): Bengt Mattsson; Malin Parmar; Anders Björklund, Publisher: Academic Press, Copyright: 2023
Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a computerized 3D environment. The maps enable readers to better calculate co-ordinates to target specific structures for toxin, virus, or cell delivery using stereotaxic surgery. This atlas will be a valuable resource for any neuroscientist who wishes to work with nude rats in experimental and pre-clinical studies.
- Contains coronal, sagittal, and horizontal maps of young adult athymic nude rat brain, spaced with a distance of 0.2 or 0.25 mm
- Uses “flat skull” Bregma and Lambda as anatomical landmarks for correct placement in the 3D environment
- Anatomical structures and nomenclature follow the standard set by the Paxinos and Watson rat brain atlases
- Includes a map of the dopamine projection system as well as the distribution of the A8-A14 dopamine cell groups
- Allows for easy read-out of coordinates for precise injections using stereotactic surgery
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